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Rapamycin enhances the anti-tumor activity of cabozantinib in cMet inhibitor-resistant hepatocellular carcinoma

Frontiers of Medicine 2022, Volume 16, Issue 3,   Pages 467-482 doi: 10.1007/s11684-021-0869-y

Abstract: However, the lower response rate and resistance limit its enduring clinical benefit.In this study, we found that cMet-low HCC cells showed primary resistance to cMet inhibitors, and the

Keywords: hepatocellular carcinoma     cabozantinib     primary resistance     rapamycin    

Evaluation of power regeneration in primary suspension for a railway vehicle

Ruichen WANG, Zhiwei WANG

Frontiers of Mechanical Engineering 2020, Volume 15, Issue 2,   Pages 265-278 doi: 10.1007/s11465-019-0571-9

Abstract: rail vehicles, this study presents the feasibility of using power regenerating dampers (PRDs) in the primaryPRDs are configured as hydraulic electromagnetic-based railway primary vertical dampers and evaluatedof the generator, and the electromagnetic configuration provides a controllable damping force to the primaryIn several case studies, generic railway vehicle primary suspension systems that are configured to includeResults indicate that PRDs can simultaneously replace conventional primary vertical dampers, regenerate

Keywords: railway vehicle     primary damper     power regeneration     ride comfort     running safety    

Dynein axonemal heavy chain 10 deficiency causes primary ciliary dyskinesia in humans and mice

Frontiers of Medicine   Pages 957-971 doi: 10.1007/s11684-023-0988-8

Abstract: Primary ciliary dyskinesia (PCD) is a congenital, motile ciliopathy with pleiotropic symptoms.

Keywords: DNAH10     mice     motile cilia     mutation     primary ciliary dyskinesia    

Approach for natural gas to be a primary energy source in China

Weihe HUANG, Jindian CHEN, Chuan FU, Yan HUANG

Frontiers of Engineering Management 2019, Volume 6, Issue 4,   Pages 467-476 doi: 10.1007/s42524-019-0068-6

Abstract: In the long-term adjustment of energy structure, natural gas has gradually become the primary energyFor natural gas to be the primary energy, the exploitation of gas resources must be expanded, resource

Keywords: natural gas     energy revolution     primary energy     utilization areas     approaching means    

Effect of traditional Chinese medicine combined with Western therapy on primary hepatic carcinoma: a

Li Ma, Bin Wang, Yuanxiong Long, Hanmin Li

Frontiers of Medicine 2017, Volume 11, Issue 2,   Pages 191-202 doi: 10.1007/s11684-017-0512-0

Abstract:

Primary hepatic carcinoma (PHC) is a common malignant tumor in China.systematic review with meta-analysis aimed to assess the effect of TCM combined with Western therapy on primary

Keywords: traditional Chinese medicine     primary hepatic carcinoma     meta-analysis    

Tuning the primary selective nanochannels of MOF thin-film nanocomposite nanofiltration membranes for

Frontiers of Environmental Science & Engineering 2022, Volume 16, Issue 4, doi: 10.1007/s11783-021-1474-7

Abstract:

• PA layer properties tune the primary nanochannels in MIL-101(Cr) TFN

Keywords: Porous metal organic framework     Thin-film nanocomposite membrane     Primary selective nanochannels     Nanofiltration    

Primary hypertrophic osteoarthropathy: an update

Zeng Zhang, Changqing Zhang, Zhenlin Zhang

Frontiers of Medicine 2013, Volume 7, Issue 1,   Pages 60-64 doi: 10.1007/s11684-013-0246-6

Abstract: The study of a clinically indistinguishable idiopathic form (primary hypertrophic osteoarthropathy, PHO

Keywords: digital clubbing     primary hypertrophic osteoarthropathy     prostaglandin E2 (PGE2)    

Case report of neurofibromatosis type 1 combined with primary ciliary dyskinesia

Frontiers of Medicine 2021, Volume 15, Issue 6,   Pages 933-937 doi: 10.1007/s11684-021-0860-7

Abstract: with his early-onset wet cough, sinusitis, and sperm quality decline, we considered the possibility of primary

Keywords: primary ciliary dyskinesia     neurofibromatosis     bronchiectasis     transmission electron microscopy     genetic    

Diagnostic evaluation of plasma aldosterone concentration to plasma renin activity ratio in primary aldosteronism

ZHANG Huilan, WANG Daowen

Frontiers of Medicine 2008, Volume 2, Issue 1,   Pages 11-14 doi: 10.1007/s11684-008-0003-4

Abstract: aldosterone concentration to plasma renin activity ratio (PAC/PRA ratio) as the screening test of choice for primaryhypertensive patients, we studied the clinical characteristics and the diagnostic value of PAC/PRA ratio in primaryOne hundred and twenty-six suspected primary aldosteronism patients whose PAC/PRA ratio was > 25 ng/dLThe proportion of primary aldosteronism in hypertensive patients was 14% (126/902).Primary aldosteronism affects over 10% of hypertensive patients in China.

Lack of CFAP54 causes primary ciliary dyskinesia in a mouse model and human patients

Frontiers of Medicine doi: 10.1007/s11684-023-0997-7

Abstract: Primary ciliary dyskinesia (PCD) is a highly heterogeneous recessive inherited disorder.

Keywords: primary ciliary dyskinesia     CFAP54     cilia    

Health: a dream from reality to the future

Chunsong Hu,Qinghua Wu

Frontiers of Medicine 2016, Volume 10, Issue 2,   Pages 233-235 doi: 10.1007/s11684-016-0444-0

Abstract: developments and the source of a person’s and his/her family’s happiness, health requires not only primary

Keywords: health promotion     primary and secondary prevention     policy prevention     infectious disease     non-communicable    

Primary cilia in hard tissue development and diseases

Frontiers of Medicine 2021, Volume 15, Issue 5,   Pages 657-678 doi: 10.1007/s11684-021-0829-6

Abstract: Primary cilia are protrusions on the surfaces of cells.Furthermore, primary cilia act as sensors of external stimuli and regulate bone homeostasis.Specifically, substances are trafficked through primary cilia by intraflagellar transport, which affectsIn this review, we summarize the roles of primary cilia in long bone development and remodeling fromtwo perspectives: primary cilia signaling and sensory mechanisms.

Keywords: primary cilia     bone     mechanical sensing     hard tissue     cilium-related bone disease     tooth    

β-Cyclodextrin promoted oxidation of primary amines to nitriles in water

Dongpo SHI, Hongbing JI, Zhong LI

Frontiers of Chemical Science and Engineering 2009, Volume 3, Issue 2,   Pages 196-200 doi: 10.1007/s11705-009-0051-6

Abstract: A facile, efficient and substrate-selective oxidation of the primary amines with NaClO as oxidant catalyzedhas been developed in water for the first time, and the behavior of cyclodextrin that catalyzed the primaryIt was found that the primary amines which could form host-guest complexes with cyclodextrin were oxidized

Keywords: substrate-selective     amines oxidation     β-cyclodextrin    

System construction of a four-side primary permanent-magnet linear motor drive mechanical press

Jintao LIANG, Zhengfeng MING, Peida LI

Frontiers of Mechanical Engineering 2020, Volume 15, Issue 4,   Pages 600-609 doi: 10.1007/s11465-020-0597-z

Abstract: A primary permanent-magnet linear motor (PPMLM) has a robust secondary structure and high force density

Keywords: mechanical press     direct drive     primary permanent-magnet linear motor (PPMLM)     servo system     active disturbance    

Prevalence of antifolate drug resistance markers in in China

Frontiers of Medicine 2022, Volume 16, Issue 1,   Pages 83-92 doi: 10.1007/s11684-021-0894-x

Abstract: dhfr) and dihydropteroate synthetase (dhps) genes of Plasmodium vivax and antifolate resistance-associatedgenes were used for drug resistance surveillance.This study indicated that the antifolate resistance levels of P. vivax parasites were differentacross China and molecular markers could be used to rapidly monitor drug resistance.

Keywords: drug resistance     antifolates     molecular markers     Plasmodium vivax     China    

Title Author Date Type Operation

Rapamycin enhances the anti-tumor activity of cabozantinib in cMet inhibitor-resistant hepatocellular carcinoma

Journal Article

Evaluation of power regeneration in primary suspension for a railway vehicle

Ruichen WANG, Zhiwei WANG

Journal Article

Dynein axonemal heavy chain 10 deficiency causes primary ciliary dyskinesia in humans and mice

Journal Article

Approach for natural gas to be a primary energy source in China

Weihe HUANG, Jindian CHEN, Chuan FU, Yan HUANG

Journal Article

Effect of traditional Chinese medicine combined with Western therapy on primary hepatic carcinoma: a

Li Ma, Bin Wang, Yuanxiong Long, Hanmin Li

Journal Article

Tuning the primary selective nanochannels of MOF thin-film nanocomposite nanofiltration membranes for

Journal Article

Primary hypertrophic osteoarthropathy: an update

Zeng Zhang, Changqing Zhang, Zhenlin Zhang

Journal Article

Case report of neurofibromatosis type 1 combined with primary ciliary dyskinesia

Journal Article

Diagnostic evaluation of plasma aldosterone concentration to plasma renin activity ratio in primary aldosteronism

ZHANG Huilan, WANG Daowen

Journal Article

Lack of CFAP54 causes primary ciliary dyskinesia in a mouse model and human patients

Journal Article

Health: a dream from reality to the future

Chunsong Hu,Qinghua Wu

Journal Article

Primary cilia in hard tissue development and diseases

Journal Article

β-Cyclodextrin promoted oxidation of primary amines to nitriles in water

Dongpo SHI, Hongbing JI, Zhong LI

Journal Article

System construction of a four-side primary permanent-magnet linear motor drive mechanical press

Jintao LIANG, Zhengfeng MING, Peida LI

Journal Article

Prevalence of antifolate drug resistance markers in in China

Journal Article